Acetamide, N-[(2S)-2-(acetyloxy)-3-chloropropyl]-
- CasNo:183905-31-9
Product Description
Quality Factory Supply 99% Pure Acetamide, N-[(2S)-2-(acetyloxy)-3-chloropropyl]- 183905-31-9 with Efficient Delivery
- Molecular Formula: C7H12ClNO3
- Molecular Weight: 193.63
- Boiling Point: 370.249 °C at 760 mmHg
- PKA: 15.42±0.46(Predicted)
- Flash Point: 177.721 °C
- PSA: 58.89000
- Density: 1.172 g/cm3
- LogP: 1.13330
183905-31-9 Relevant articles
Diol-Ritter Reaction: Regio- And Stereoselective Synthesis of Protected Vicinal Aminoalcohols and Mechanistic Aspects of Diol Monoester Disproportionation
Abboud, Khalil A.,Cheng, Kevin,Klosin, Jerzy,Kruper, William J.,Kruper, William R.,Lysenko, Ivan,Ondari, Mark E.,Thomas, Pulikkottil J.
, (2021/10/20)
The well-known epoxide-Ritter reaction g...
Environment-friendly synthesis method of linezolid and intermediate thereof
-
Paragraph 0043; 0044; 0045, (2018/11/22)
The invention relates to a more environm...
OXAZOLIDINONE COMPOUNDS AND METHODS OF USE THEREOF AS ANTIBACTERIAL AGENTS
-
Page/Page column 46; 47, (2017/05/19)
The present invention relates to oxazoli...
the advantage cuts down Sha Ban and intermediate preparation method
-
Paragraph 0074; 0082; 0083, (2017/07/31)
The present invention discloses a new me...
183905-31-9 Process route
-
-
108-24-7
acetic anhydride
-
-
34839-13-9,54798-66-2
(2S)-1-amino-3-chloropropan-2-ol hydrogen chloride
-
-
183905-31-9
N-[(2S)-2-acetoxy-3-chloropropyl]acetamide
| Conditions | Yield |
|---|---|
|
With
pyridine;
In
dichloromethane;
at 20 - 40 ℃;
for 22h;
|
89%
|
|
With
pyridine;
In
dichloromethane;
at 18 - 40 ℃;
for 5h;
|
75%
|
|
With
pyridine;
at 20 ℃;
|
47.98%
|
|
|
|
|
With
pyridine;
at 20 ℃;
|
50.2 g
|
|
acetic anhydride; (2S)-1-amino-3-chloropropan-2-ol hydrogen chloride;
With
pyridine;
In
dichloromethane;
at 35 ℃;
for 16h;
With
potassium carbonate;
In
dichloromethane;
at 5 - 7 ℃;
|
-
-
34839-13-9,54798-66-2
(S)-1-amino-3-chloro-2-propanol hydrochloride
-
-
75-36-5
acetyl chloride
-
-
183905-31-9
N-[(2S)-2-acetoxy-3-chloropropyl]acetamide
| Conditions | Yield |
|---|---|
|
With
pyridine;
In
dichloromethane;
at 0 - 20 ℃;
for 10h;
|
86.1%
|
183905-31-9 Upstream products
-
108-24-7
acetic anhydride
-
53494-57-8
(S)-1-amino-3-chloropropan-2-ol
-
34839-13-9
(2S)-1-amino-3-chloropropan-2-ol hydrogen chloride
-
34839-13-9
(S)-1-amino-3-chloro-2-propanol hydrochloride
183905-31-9 Downstream products
-
183805-10-9
N-[(2S)oxiranylmethyl]acetamide
-
444587-58-0
benzyl 7-{(5S)-5-[(acetylamino)methyl]-2-oxo-1,3-oxazolidin-3-yl}-1,2,4,5-tetrahydro-3H-3-benzazepine-3-carboxylate
-
444588-20-9
phenylmethyl-7-{5-[(acetamino)methyl]-2-oxo-1,3-oxazolidin-3-yl}-2H,3H,4H,5H-benzo[f]azaperhydroepinecarboxylate
-
444588-30-1
benzyl 7-{(5S)-5-[(acetylamino)methyl]-2-oxo-1,3-oxazolidin-3-yl}-1,3,4,5-tetrahydro-3H-2-benzazepine-2-carboxylate