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Acetamide, N-[(2S)-2-(acetyloxy)-3-chloropropyl]-

  • CasNo:183905-31-9

Product Description

Quality Factory Supply 99% Pure Acetamide, N-[(2S)-2-(acetyloxy)-3-chloropropyl]- 183905-31-9 with Efficient Delivery

  • Molecular Formula: C7H12ClNO3
  • Molecular Weight: 193.63
  • Boiling Point: 370.249 °C at 760 mmHg 
  • PKA: 15.42±0.46(Predicted) 
  • Flash Point: 177.721 °C 
  • PSA: 58.89000 
  • Density: 1.172 g/cm3 
  • LogP: 1.13330 

183905-31-9 Relevant articles

Diol-Ritter Reaction: Regio- And Stereoselective Synthesis of Protected Vicinal Aminoalcohols and Mechanistic Aspects of Diol Monoester Disproportionation

Abboud, Khalil A.,Cheng, Kevin,Klosin, Jerzy,Kruper, William J.,Kruper, William R.,Lysenko, Ivan,Ondari, Mark E.,Thomas, Pulikkottil J.

, (2021/10/20)

The well-known epoxide-Ritter reaction g...

Environment-friendly synthesis method of linezolid and intermediate thereof

-

Paragraph 0043; 0044; 0045, (2018/11/22)

The invention relates to a more environm...

OXAZOLIDINONE COMPOUNDS AND METHODS OF USE THEREOF AS ANTIBACTERIAL AGENTS

-

Page/Page column 46; 47, (2017/05/19)

The present invention relates to oxazoli...

the advantage cuts down Sha Ban and intermediate preparation method

-

Paragraph 0074; 0082; 0083, (2017/07/31)

The present invention discloses a new me...

183905-31-9 Process route

acetic anhydride
108-24-7

acetic anhydride

(2S)-1-amino-3-chloropropan-2-ol hydrogen chloride
34839-13-9,54798-66-2

(2S)-1-amino-3-chloropropan-2-ol hydrogen chloride

N-[(2S)-2-acetoxy-3-chloropropyl]acetamide
183905-31-9

N-[(2S)-2-acetoxy-3-chloropropyl]acetamide

Conditions
Conditions Yield
With pyridine; In dichloromethane; at 20 - 40 ℃; for 22h;
89%
With pyridine; In dichloromethane; at 18 - 40 ℃; for 5h;
75%
With pyridine; at 20 ℃;
47.98%
With pyridine; at 20 ℃;
50.2 g
acetic anhydride; (2S)-1-amino-3-chloropropan-2-ol hydrogen chloride; With pyridine; In dichloromethane; at 35 ℃; for 16h;
With potassium carbonate; In dichloromethane; at 5 - 7 ℃;
(S)-1-amino-3-chloro-2-propanol hydrochloride
34839-13-9,54798-66-2

(S)-1-amino-3-chloro-2-propanol hydrochloride

acetyl chloride
75-36-5

acetyl chloride

N-[(2S)-2-acetoxy-3-chloropropyl]acetamide
183905-31-9

N-[(2S)-2-acetoxy-3-chloropropyl]acetamide

Conditions
Conditions Yield
With pyridine; In dichloromethane; at 0 - 20 ℃; for 10h;
86.1%

183905-31-9 Upstream products

  • 108-24-7
    108-24-7

    acetic anhydride

  • 53494-57-8
    53494-57-8

    (S)-1-amino-3-chloropropan-2-ol

  • 34839-13-9
    34839-13-9

    (2S)-1-amino-3-chloropropan-2-ol hydrogen chloride

  • 34839-13-9
    34839-13-9

    (S)-1-amino-3-chloro-2-propanol hydrochloride

183905-31-9 Downstream products

  • 183805-10-9
    183805-10-9

    N-[(2S)oxiranylmethyl]acetamide

  • 444587-58-0
    444587-58-0

    benzyl 7-{(5S)-5-[(acetylamino)methyl]-2-oxo-1,3-oxazolidin-3-yl}-1,2,4,5-tetrahydro-3H-3-benzazepine-3-carboxylate

  • 444588-20-9
    444588-20-9

    phenylmethyl-7-{5-[(acetamino)methyl]-2-oxo-1,3-oxazolidin-3-yl}-2H,3H,4H,5H-benzo[f]azaperhydroepinecarboxylate

  • 444588-30-1
    444588-30-1

    benzyl 7-{(5S)-5-[(acetylamino)methyl]-2-oxo-1,3-oxazolidin-3-yl}-1,3,4,5-tetrahydro-3H-2-benzazepine-2-carboxylate

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